I show how to connect to a named instance using PolyBase in SQL Server 2019 or 2022:
We have two SQL Server instances running on the same machine. Before we get started, I do want to point out one thing: PolyBase can only work on one instance for a given server (physical machine or virtual machine) because the PolyBase engine and data movement services are system-level services. This means you cannot have PolyBase installed on your main instance as well as your named instance.
Click through for two methods.