Jason Brimhall shows how you can use Extended Events to figure out if that database is still in use:
Here we can see there are indeed some databases that are still in use on this server. If we are looking to retire the instance, or migrate relevant databases to a new server, we have better information about how to go about planning that work. Based on this data, I would be able to retire the ProtossZealot database but would be required to do something with the ZergRush and BroodWar databases. In the case of the ProtossZealot database that is not being used, we now have evidence to present back to the team that the database is not used. It is now up to those insisting on keeping it around to justify its existence and document why it must remain in tact.
Click through for the script Jason used to determine this.