This has led to the belief (or at least I believe this is one of the causes) that you can only restore a single differential backup. And up until the last few weeks I’d believed that myself. So, to set up a fairly simple test. I’m going to take a backup, create a table, and make some changes with differential backups in between the changes.
Check it out. I don’t really see a good case for restoring multiple differentials (because each differential has the complete set of changes since the last full backup, so the differential at X+t is a proper subset of X+2t if your goal is to restore back to X+2t), but having multiple differentials, absolutely.