You are probably already aware that you can disable an index. This can be handy when you have a large load and the load + re-enabling the indexes (you have to completely rebuild them) is faster than leaving the indexes in place. I’ve had pretty limited occasions where this has helped but it can be a handy trick at times. That said, this is only true for non-clustered indexes. What happens when you disable the clustered index?
Nothing good, that’s what.