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NUMA With Few Cores

Denny Cherry asks and answers the question of how many NUMA nodes we should use on a server with a large amount of RAM but relatively few cores:

For this example, let’s assume that we have a physical server with 512 Gigs of RAM and two physical NUMA nodes (and two CPU sockets). We have a VM running in that machine which has a low CPU requirement, but a large working set. Because of this we have 4 cores and 360 Gigs of RAM presented to the VM.

The answer is not trivial, making this an interesting question.