Bioconductor in the Wake of ggplot2 4.0.0

Maria Doyle lays it out:

A major update to ggplot2 (version 4.0.0) is expected around mid-to-late July 2025. It brings a significant internal change, replacing most of the S3 backend with the newer S7 object system. While this improves long-term maintainability and extensibility, it may break Bioconductor packages that depend on ggplot2, especially those that customise how plots are built or styled. Packages that use ggplot2 for typical plotting tasks, such as creating plots with ggplot() and geom_*(), are unlikely to be affected.

Click through for notes, tips on what to do, and whether the code you’re using will break with ggplot2 4.0.0. H/T R-Bloggers.