When we are about to enable a new feature, one of the first things we have to check is whether enabling this feature will break the existing code. Enabling this feature could bring two breaking changes: one is related to columnstore indexes, the other to transactions with memory-optimized tables.
I don’t think these limitations are that game-breaking, but if you’re regularly loading large tables in tempdb and using columnstore indexes on them, you might be in for a nasty surprise.