Brent Ozar gives us some good pointers on when to use Always Encrypted:
But that comes with a few big drawbacks. They’re really well-documented, but here’s the highlights:
Do you need to query that data from other apps? Do you have a data warehouse, reporting tools, PowerBI, Analysis Services cubes, etc? If so, those apps will also need to be equipped with the latest database drivers and your decryption certificates. For example, here’s how you access Always Encrypted data with PowerBI. Any app that expects to read the encrypted data is going to need work, and that’s especially problematic if you’re replicating the data to other SQL Servers.
Click through to read the rest. Always Encrypted was designed to encrypt a few columns, not everything in a database.