Wayne Sheffield has an article on I/O partition alignment:
What we need to do is to offset the beginning of the data being stored on disk to a location more conducive to how the program is operating. This offset is known as the “Partition Alignment Offset”. To be in tune with SQL Server, this value should be an increment of 64KB. However, you also need to consider the entire storage subsystem – the disks, controllers and memory. Starting with Windows Server 2008, this offset is at 1024KB – a nice increment of 64KB that also works very nicely with most RAID disks/controllers. Prior to Windows Server 2008, partition alignment offset was not explicitly performed, so this will need to be performed.
If you’ve migrated disk from server to server to server over the years, this is worth checking out.