You can now use Always Encrypted with the Microsoft ODBC Driver 13.1 for SQL Server. Always Encrypted is a new SQL Server 2016 and Azure SQL Database security feature that prevents sensitive data from being seen in plaintext in a SQL instance. You can now transparently encrypt the data in the application, so that SQL Server or Azure SQL Database will only handle the encrypted data and not plaintext values. If a SQL instance or host machine is compromised, an attacker can only access ciphertext of your sensitive data. Use the ODBC Driver 13.1 to encrypt plaintext data and store the encrypted data in SQL Server 2016 or Azure SQL Database. Likewise, use the driver to decrypt your encrypted data.
Check out the full list of new features at the link above.